- Letybo is a neuromodulator — a botulinum-toxin A injectable (active ingredient: letibotulinumtoxinA-wlbg). It works by temporarily blocking nerve signals that cause muscle contraction, thus relaxing the muscles that create expression wrinkles (like frown lines between the brows).
- In the U.S., Letybo is FDA-approved for the treatment of moderate to severe glabellar lines (the “11” lines / frown lines between eyebrows) in adults.
- According to clinical trials, the onset of visible improvement can occur as early as 2–3 days after injection, with many patients seeing results by day 3.
- The effects typically last about 3–4 months (roughly 12–16 weeks), similar to other neuromodulators on the market (like Botox, Dysport, Xeomin).
- Advantages that are often highlighted: a “cleaner” or highly purified formulation (which may reduce the risk of developing antibodies over time), and potentially a slightly faster onset and more precise diffusion — beneficial when treating small areas or aiming for subtle, natural-looking results.
That said — and this is important — the potency units of Letybo are not interchangeable with other botulinum toxin products, so dosing and technique must be handled with care.
Bottom line: Letybo offers a promising, modern alternative to more established injectables — potentially less expensive, with a well-documented safety profile and results comparable to existing options.
Who is Dr. Karen Singer — A seasoned plastic surgeon in St. Petersburg, FL
- Dr. Karen Singer, M.D., is a board-certified plastic surgeon based in St. Petersburg, Florida, practicing through her clinic at 4021 Central Ave Ste A, St. Petersburg, FL 33713.
- Her background: undergraduate (Magna Cum Laude, Highest Honors) at Harvard University; MD degree from Harvard Medical School; general surgery training at Roosevelt Hospital (NYC), followed by plastic surgery specialization at St. Barnabas Medical Center (New Jersey); plus a fellowship in hand surgery at the University of Colorado Health Sciences Center.
- She’s been practicing plastic surgery in the Tampa Bay / St. Petersburg area for decades.
- Her practice emphasizes combining rigorous medical training with an artist’s eye for proportion, form, symmetry — whether for subtle refinements or more dramatic changes.
- Services she offers include (but are not limited to): body contouring / liposuction, blepharoplasty, breast augmentation, mastopexy, abdominoplasty, and more — using advanced techniques including power-assisted liposuction, laser-assisted lipo, tumescent liposuction, etc.
Patient reviews of Dr. Singer reflect a reputation for thoroughness, care, good results, and personalized attention. For example:
“Dr. Karen Singer listened carefully to what I wanted and took her time adding lip filler while stopping and showing me in the mirror along the way so I could approve of each step. I love the natural results!”
“Dr Singer is so professional and caring… I am so happy to find her as my doctor…”
Overall, she combines strong surgical credentials with sensitivity to aesthetic balance — valuing both safety and artistry.
Why Letybo + an experienced surgeon like Dr. Singer might appeal — and what to ask
Because you’re in Tampa, FL (near St. Petersburg), it’s reasonable to wonder if a provider like Dr. Singer might offer Letybo (or similar injectables / surgical + non-surgical combos). Here’s why that pairing could make sense — and what to check carefully.
Potential appeal:
- New alternative: Letybo brings a newer FDA-approved option to the U.S. population — for someone trying neuromodulators for the first time, or someone seeking a possibly lower-cost or more purified toxin.
- Experienced hands: With decades of experience, a board-certified background, and a strong aesthetic sensibility, Dr. Singer administers injections or surgical procedures carefully — which is especially important with newer products whose diffusion, dosing, and execution might differ from legacy toxins.
- Comprehensive aesthetic care: If you are considering both injectables and more substantial body contouring or surgical procedures, a full-service plastic surgeon allows integrated planning.
Final Thoughts: A New Era of Choice — But Do Your Homework
The arrival of Letybo in the U.S. injectables market represents the continuing evolution of cosmetic medicine. Having more options (especially newer, highly purified neuromodulators with global track records) gives patients and providers more flexibility.
Yet — as with any medical treatment — the benefits depend heavily on who is administering it, how it’s dosed/injected, and whether it’s appropriate for you personally. That’s why pairing a new option like Letybo with a seasoned, board-certified plastic surgeon, like Dr. Karen Singer, offers a strong balance of innovation, safety, and aesthetic sense.
